Partnerships & Careers

Job Description

• Establish, operate, maintain and standardize the neurophysiology research platform, and proficiently perform core techniques such as whole-cell patch-clamp, single-channel patch-clamp and field potential recording, and develop and optimize SOPs
• Perform electrophysiological experiments on cells and brain slices related to neuropharmacology and neurological diseases, complete data acquisition, analysis and interpretation, and generate reliable efficacy and mechanism-of-action data
• Support novel drug discovery projects by designing neurophysiological protocols and evaluating candidate compounds for selectivity, specificity and potential toxicity-related electrophysiological effects
• Maintain routine culture, identification and quality control of experimental cells to ensure a stable experimental system. Document experimental procedures in compliance with guidelines, compile raw data, write experimental reports and support project meetings and technical discussions
• Participate in the preparation of materials for patent filing, IND submission and pharmacology documentation, ensuring complete, traceable and regulatory-compliant experimental data
• Keep updated on advanced technologies and methodologies in neurophysiology, and continuously optimize protocols, Mentor junior researchers in basic electrophysiological techniques and assist in building a competent research team

Job Requirements

• Master's degree or above in Biomedical Science, Pharmacology, Neuroscience, Physiology, Biophysics or related majors. Experience in electrophysiological research using neuronal cells, brain slices or ion channels is a plus
• Familiar with cell/brain slice culture and related experimental techniques; Proficient in patch-clamp electrophysiology techniques and capable of conducting independent neurophysiological experiments
• Skilled in data processing and analysis using Clampfit, Origin, GraphPad and other analytical software
• Understanding of neuropharmacology, neurological disease mechanisms and drug R&D processes, with a strong interest in ion channel target research
• Strong ability in experimental design, problem analysis and independent troubleshooting. Diligent, meticulous and responsible, with strict compliance to laboratory safety and SOPs
• Good teamwork and communication skills to support cross-functional project collaboration. Quick learner and self-motivated, with a focus on tracking field advances